作者
Hale B Caglar, Roy B Tishler, Megan Othus, Elaine Burke, Yi Li, Laura Goguen, Lori J Wirth, Robert I Haddad, Carl M Norris, Laurence E Court, Donald J Aninno, Marshall R Posner, Aaron M Allen
发表日期
2008/11/15
期刊
International Journal of Radiation Oncology* Biology* Physics
卷号
72
期号
4
页码范围
1110-1118
出版商
Elsevier
简介
PURPOSE
To evaluate early swallowing after intensity-modulated radiotherapy for head-and-neck squamous cell carcinoma and determine factors correlating with aspiration and/or stricture.
METHODS AND MATERIALS
Consecutive patients treated with intensity-modulated radiotherapy with or without chemotherapy between September 2004 and August 2006 at the Dana Farber Cancer Institute/Brigham and Women's Hospital were evaluated with institutional review board approval. Patients underwent swallowing evaluation after completion of therapy; including video swallow studies. The clinical- and treatment-related variables were examined for correlation with aspiration or strictures, as well as doses to the larynx, pharyngeal constrictor muscles, and cervical esophagus. The correlation was assessed with logistic regression analysis.
RESULTS
A total of 96 patients were evaluated. Their median age was 55 …
引用总数
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