作者
Michael Heung, Diane E Steffick, Kara Zivin, Brenda W Gillespie, Tanushree Banerjee, Chi-yuan Hsu, Neil R Powe, Meda E Pavkov, Desmond E Williams, Rajiv Saran, Vahakn B Shahinian, Yi Li, Jennifer Bragg-Gresham, Vahakn Shahinian, Hal Morgenstern, Diane Steffick, Anca Tilea, Brenda Gillespie, William Herman, Jerry Yee, William McClellan, Deb Gipson, Sai Dharmarajan, Rajesh Balkrishnan, April Wyncott, Neil Powe, Kirsten Bibbins-Domingo, Deidra Crews, Vanessa Grubbs, Delphine Tuot, Yunno Zhu, Nilka Ríos Burrows, Desmond Williams, Mark Eberhardt, Paul Eggers, Meda Pavkov, Deborah Rolka, Sharon Saydah, Larry Waller
发表日期
2016/5/1
期刊
American Journal of Kidney Diseases
卷号
67
期号
5
页码范围
742-752
出版商
WB Saunders
简介
Background
Studies suggest an association between acute kidney injury (AKI) and long-term risk for chronic kidney disease (CKD), even following apparent renal recovery. Whether the pattern of renal recovery predicts kidney risk following AKI is unknown.
Study Design
Retrospective cohort.
Setting & Participants
Patients in the Veterans Health Administration in 2011 hospitalized (>24 hours) with at least 2 inpatient serum creatinine measurements, baseline estimated glomerular filtration rate > 60 mL/min/1.73 m2, and no diagnosis of end-stage renal disease or non−dialysis-dependent CKD: 17,049 (16.3%) with and 87,715 without AKI.
Predictor
Pattern of recovery to creatinine level within 0.3 mg/dL of baseline after AKI: within 2 days (fast), in 3 to 10 days (intermediate), and no recovery by 10 days (slow or unknown).
Outcome
CKD stage 3 or higher, defined as 2 outpatient estimated glomerular filtration rates < 60 mL …
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