作者
Fan Wu, Sehee Kim, Jing Qin, Rajiv Saran, Yi Li
发表日期
2018/3
期刊
Biometrics
卷号
74
期号
1
页码范围
100-108
简介
Survival data collected from a prevalent cohort are subject to left truncation and the analysis is challenging. Conditional approaches for left‐truncated data could be inefficient as they ignore the information in the marginal likelihood of the truncation times. Length‐biased sampling methods may improve the estimation efficiency but only when the underlying truncation time is uniform; otherwise, they may generate biased estimates. We propose a semiparametric method for left‐truncated data under the Cox model with no parametric distributional assumption about the truncation times. Our approach is to make inference based on the conditional likelihood augmented with a pairwise likelihood, which eliminates the truncation distribution, yet retains the information about the regression coefficients and the baseline hazard function in the marginal likelihood. An iterative algorithm is provided to solve for the regression …
引用总数
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