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Cover: This month s cover highlights the Research Article Pooled-matrix protein interaction screens using Barcode Fusion Genetics by Nozomu Yachie, Evangelia Petsalaki, Frederick P. Roth and colleagues. The cover illustrates the key concept of barcode fusion genetics: intracellular fusion of two connected DNA barcodes to represent the combination of proteins that participate in a protein interaction. Cover art by Uta Mackensen, in consultation with the authors.