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ContextDespite federal regulations on faculty conflicts of interest in federally funded research, academic-industry ties are common, and evidence exists that financial considerations bias the research record. Public scrutiny of these ties is increasing, especially in cases where researchers have financial interests in the corporate sponsors of their clinical research.ObjectiveTo review policies on conflict of interest at major biomedical research institutions in the United States.DesignCross-sectional survey and content analysis study conducted from August 1998 to February 2000.Setting and ParticipantsThe 100 US institutions with the most funding from the National Institutes of Health in 1998 were initially sampled; policies from 89 institutions were available and included in the analysis.Main Outcome MeasuresProcess for disclosure, review, and management of conflicts of interest and specified management strategies or …