作者
Diabetes Prevention Program Outcomes Study Research Group; prepared on behalf of the DPPOS Research Group, TJ Orchard, M Temprosa, E Barrett‐Connor, SE Fowler, RB Goldberg, KJ Mather, SM Marcovina, M Montez, RE Ratner, CD Saudek, H Sherif, KE Watson
发表日期
2013/1
期刊
Diabetic Medicine
卷号
30
期号
1
页码范围
46-55
出版商
Blackwell Publishing Ltd
简介
Diabet. Med. 30, 46–55 (2013)
Abstract
Aims Whether long‐term cardiovascular risk is reduced by the Diabetes Prevention Program interventions is unknown. The aim of this study was to determine the long‐term differences in cardiovascular disease risk factors and the use of lipid and blood pressure medications by the original Diabetes Prevention Program intervention group.
Methods This long‐term follow‐up (median 10 years, interquartile range 9.0–10.5) of the three‐arm Diabetes Prevention Program randomized controlled clinical trial (metformin, intensive lifestyle and placebo), performed on 2766 (88%) of the Diabetes Prevention Program participants (who originally had impaired glucose tolerance), comprised a mean of 3.2 years of randomized treatment, approximately 1‐year transition (during which all participants were offered intensive lifestyle intervention) and 5 years follow‐up (Diabetes …
学术搜索中的文章
… Prevention Program Outcomes Study Research Group; … - Diabetic Medicine, 2013