作者
Hiroki Nariai, Tetsuro Nagasawa, Csaba Juhász, Sandeep Sood, Harry T Chugani, Eishi Asano
发表日期
2011/1
期刊
Epilepsia
卷号
52
期号
1
页码范围
63-74
出版商
Blackwell Publishing Ltd
简介
Purpose:  We assessed 636 epileptic spasms seen in 11 children (median 44 spasms per child) and determined the spatial and temporal characteristics of ictal high‐frequency oscillations (HFOs) in relation to the onset of spasms.
Methods:  Electrocorticography (ECoG) signals were sampled from 104–148 cortical sites per child, and the dynamic changes of ictal HFOs were animated on each individual’s three‐dimensional (3D) magnetic resonance (MR) image surface.
Key Findings:  Visual assessment of ictal ECoG recordings revealed that each spasm event was characterized by augmentation of HFOs. Time‐frequency analysis demonstrated that ictal augmentation of HFOs at 80–200 Hz was most prominent and generally preceded those at 210–300 Hz and at 70 Hz and slower. Recruitment of HFOs in the rolandic cortex preceded the clinical onset objectively visualized as electromyographic deflection …
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