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Coronary artery disease (CAD) is the most common cardiovascular disease (CVD) that cause millions of deaths worldwide due to heart failure, heart attack, and angina. The symptoms of the CAD do not appear in the early stage of the disease and it causes deadly conditions; therefore, accurate and early diagnosis of CAD is necessary to take appropriate and timely action for preventing or minimizing such conditions. Angiography, being the most accurate method for diagnosis of CAD, is often used by the clinicians to diagnose the CAD but this is an invasive procedure, costly, and may cause side effects. Therefore, researchers are trying to develop alternative diagnostic modalities for the efficient diagnosis of CAD. To that end, machine learning and data mining techniques have been widely employed. This paper proposes and develops hybrid Particle swarm optimization based Extreme learning machine (PSO-ELM …