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Wang et al. 1 have recently reported an X-ray grating interferometer imaging approach 2–4 for mammography combining the information from the X-ray absorption and small-angle scattering signal. The authors claim that their approach can distinguish between type I (calcium oxalate dihydrate, CaC2O4 42H2O) and type II (calcium hydroxyapatite, Ca5 (PO4) 3 (OH)) microcalcifications. While such a differentiation would indeed be of great value for clinical mammography, several important deficiencies in the study put the main results and conclusions of the published article in question. The shortcomings in the published work became obvious, after we have unsuccessfully tried to reproduce the results in our own laboratory.