作者
Anjali Sankar, Simon C Ziersen, Brice Ozenne, Emily E Beaman, Vibeke H Dam, Patrick M Fisher, Gitte M Knudsen, Lars V Kessing, Vibe Frokjaer, Kamilla W Miskowiak
发表日期
2023/4/1
期刊
EClinicalMedicine
卷号
58
出版商
Elsevier
简介
Background
Neurocognitive impairments are associated with poor clinical and employment outcomes in individuals with affective disorders. However, little is known about their associations with long-term clinical outcomes such as psychiatric hospitalizations, and with socio-demographic indicators other than employment. In the largest longitudinal study of neurocognition in affective disorders to date, we investigate the role of neurocognitive impairments on psychiatric hospitalizations and socio-demographic conditions.
Methods
The study included 518 individuals with bipolar or major depressive disorder. Neurocognitive assessments covered executive function and verbal memory domains. Longitudinal data on psychiatric hospitalization and socio-demographic conditions (employment, cohabitation, and marital status) for up to 11 years were obtained using National population-based registers. The primary and …
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