作者
Pan Su, Deng Mao, Peiying Liu, Yang Li, Marco C Pinho, Babu G Welch, Hanzhang Lu
发表日期
2017/11
期刊
Magnetic resonance in medicine
卷号
78
期号
5
页码范围
1812-1823
简介
Purpose
Assessment of brain hemodynamics without exogenous contrast agents is of increasing importance in clinical applications. This study aims to develop an MR perfusion technique that can provide noncontrast and multiparametric estimation of hemodynamic markers.
Methods
We devised an arterial spin labeling (ASL) method based on the principle of MR fingerprinting (MRF), referred to as MRF‐ASL. By taking advantage of the rich information contained in MRF sequence, up to seven hemodynamic parameters can be estimated concomitantly. Feasibility demonstration, flip angle optimization, comparison with Look‐Locker ASL, reproducibility test, sensitivity to hypercapnia challenge, and initial clinical application in an intracranial steno‐occlusive process, Moyamoya disease, were performed to evaluate this technique.
Results
Magnetic resonance fingerprinting ASL provided estimation of up to seven …
学术搜索中的文章
P Su, D Mao, P Liu, Y Li, MC Pinho, BG Welch, H Lu - Magnetic resonance in medicine, 2017