作者
Jamie Chung Mei Lam, Agnes Yuen Kwan Lai, Terence Chi Chun Tam, Michele Mae Ann Yuen, Karen Siu Ling Lam, Mary Sau Man Ip
发表日期
2017/5
期刊
Sleep and Breathing
卷号
21
页码范围
377-386
出版商
Springer Berlin Heidelberg
简介
Purpose
Obstructive sleep apnea (OSA) is highly associated with type 2 diabetes mellitus (DM), and treatment of OSA may have a positive impact on cardiometabolic profile. This study investigates the effects of continuous positive airway pressure (CPAP) treatment on glycemic control and cardiometabolic parameters in patients with diabetes.
Methods
Diabetic patients, who were newly diagnosed of OSA with an apnea hypopnea index (AHI) ≥15 and HbA1c ≥7%, were randomly assigned to either CPAP treatment or no treatment (control) for 3 months. Measurements included HbA1c, blood pressure, fasting glucose and lipids, urinary albumin, and peripheral arterial tonometry (to assess endothelial function).
Results
Sixty-four patients (52 men) were randomized, with mean (±SD) age of 55.0 ± 9.6 years, body mass …
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JCM Lam, AYK Lai, TCC Tam, MMA Yuen, KSL Lam… - Sleep and Breathing, 2017