作者
Stephan M Oreskovich, Frank J Ong, Basma A Ahmed, Norman B Konyer, Denis P Blondin, Elizabeth Gunn, Nina P Singh, Michael D Noseworthy, Francois Haman, Andre C Carpentier, Zubin Punthakee, Gregory R Steinberg, Katherine M Morrison
发表日期
2019/12
期刊
Journal of the Endocrine Society
卷号
3
期号
12
页码范围
2374-2384
出版商
Endocrine Society
简介
Context
In rodents, cold exposure induces the activation of brown adipose tissue (BAT) and the induction of intracellular triacylglycerol (TAG) lipolysis. However, in humans, the kinetics of supraclavicular (SCV) BAT activation and the potential importance of TAG stores remain poorly defined.
Objective
To determine the time course of BAT activation and changes in intracellular TAG using MRI assessment of the SCV (i.e., BAT depot) and fat in the posterior neck region (i.e., non-BAT).
Design
Cross-sectional.
Setting
Clinical research center.
Patients or Other Participants
Twelve healthy male volunteers aged 18 to 29 years [body mass index = 24.7 ± 2.8 kg/m2 and body fat percentage = 25.0% ± 7.4% (both, mean ± SD)].
Intervention(s)
Standardized whole-body cold exposure (180 minutes at 18°C …
学术搜索中的文章
SM Oreskovich, FJ Ong, BA Ahmed, NB Konyer… - Journal of the Endocrine Society, 2019