作者
S Mahendran, BS Thippeswamy, VP Veerapur, S Badami
发表日期
2011/1/15
期刊
Phytomedicine
卷号
18
期号
2-3
页码范围
186-188
出版商
Urban & Fischer
简介
Anticonvulsant activity of embelin (25, 50 and 100mg/kg, i.p.) was studied. It showed a significant inhibition of the seizures induced by electroshock and pentylenetetrazole in a dose dependent manner and the activity was comparable to phenytoin and diazepam. Significant decrease in locomotion revealing its CNS depressant activity was observed. The findings suggest that embelin possess anticonvulsant activity against both grand mal and petit mal epilepsy.
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