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To review the literature on pheochromocytoma in pregnancy (PIP) published during the 11-year period 1998 through 2008.

We searched MEDLINE data sources from 1998 through 2008 using the search terms “pheochromocytoma” and “pregnancy” and reviewed case reports of PIP published in English.

We identified 54 case reports in MEDLINE data sources, of which 51 reports including 60 cases were reviewed. In comparison with the previous decade, a decreased rate of antenatal diagnosis (from 83% to 70%) and increased maternal and fetal mortality (from 4% to 12% and from 10% to 17%, respectively) were observed. Prematurity was present in 53% of the infants of mothers with antenatally diagnosed pheochromocytoma who gave birth to a live infant. Hypertension was the most common manifestation (88%), with 33% of patients having antepartum hypertensive crises. Urinary …