作者
Andrew J Vickers, Angel M Cronin, Alexandra C Maschino, George Lewith, Hugh MacPherson, Nadine E Foster, Karen J Sherman, Claudia M Witt, Klaus Linde, for the Acupuncture Trialists' Collaboration
发表日期
2012/10/22
来源
Archives of internal medicine
卷号
172
期号
19
页码范围
1444-1453
出版商
American Medical Association
简介
Background
Although acupuncture is widely used for chronic pain, there remains considerable controversy as to its value. We aimed to determine the effect size of acupuncture for 4 chronic pain conditions: back and neck pain, osteoarthritis, chronic headache, and shoulder pain.
Methods
We conducted a systematic review to identify randomized controlled trials (RCTs) of acupuncture for chronic pain in which allocation concealment was determined unambiguously to be adequate. Individual patient data meta-analyses were conducted using data from 29 of 31 eligible RCTs, with a total of 17 922 patients analyzed.
Results
In the primary analysis, including all eligible RCTs, acupuncture was superior to both sham and no-acupuncture control for each pain condition (P < .001 for all comparisons). After exclusion of an outlying set of RCTs that strongly favored acupuncture, the effect sizes were similar across pain …
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AJ Vickers, AM Cronin, AC Maschino, G Lewith… - Archives of internal medicine, 2012