作者
Sreemukta Acharya, Mark Hartmann, Sylvia Erhardt
发表日期
2017/11
来源
Wiley Interdisciplinary Reviews: RNA
卷号
8
期号
6
页码范围
e1435
出版商
John Wiley & Sons, Inc.
简介
Noncoding RNAs (ncRNAs) have emerged as crucial players in chromatin regulation. Their diversity allows them to partake in the regulation of numerous cellular processes across species. During development, long and short ncRNAs act in conjunction with each other where long ncRNAs (lncRNAs) are best understood in establishing appropriate gene expression patterns, while short ncRNAs (sRNAs) are known to establish constitutive heterochromatin and suppress mobile elements. Additionally, increasing evidence demonstrates roles of sRNAs in several typically lncRNA‐mediated processes such as dosage compensation, indicating a complex regulatory network of noncoding RNAs. Together, various ncRNAs establish many mitotically heritable epigenetic marks during development. Additionally, they participate in mechanisms that regulate maintenance of these epigenetic marks during the lifespan of the …
引用总数
201820192020202120222023241131
学术搜索中的文章
S Acharya, M Hartmann, S Erhardt - Wiley Interdisciplinary Reviews: RNA, 2017