作者
Lorenzo Busoni, Aurélie Dupont, Clémentine Symonds, Jacques Prost, Giovanni Cappello
发表日期
2006/8/4
期刊
Journal of Physics: Condensed Matter
卷号
18
期号
33
页码范围
S1957
出版商
IOP Publishing
简介
Kinesin is a dimeric molecular motor, which processively moves along the microtubule in a sequence of 8 nm steps. The stepping dynamics needs to be clarified: there are controversial reports about the existence of substructures in the mechanical step and the step timescale. We present observations of the kinesin steps in the absence of external forces, measured with subnanometre precision and microsecond time resolution using a technique which we have recently introduced and named travelling wave tracking. The data suggest that, at zero load, the 8 nm step occurs in less than 30 µs and without any long mechanical substeps.
引用总数
20062007200820092010201120122013201420152016201720182019202020212022202332111
学术搜索中的文章
L Busoni, A Dupont, C Symonds, J Prost, G Cappello - Journal of Physics: Condensed Matter, 2006