作者
Susan A Wang, Rachel B Levine, Loretta A Carson, Matthew J Arduino, Teresa Killar, F Gregory Grillo, Michele L Pearson, William R Jarvis
发表日期
1999/11
期刊
Infection Control & Hospital Epidemiology
卷号
20
期号
11
页码范围
746-751
出版商
Cambridge University Press
简介
Objective
To investigate an outbreak of gram-negative bacteremias at a hemodialysis center (December 1, 1996-January 31, 1997).
Design
Retrospective cohort study. Reviewed infection control practices and maintenance and disinfection procedures for the water system and dialysis machines. Performed cultures of the water and dialysis machines, including the waste-handling option (WHO), a drain port designed to dispose of saline used to flush the dialyzer before patient use. Compared isolates by pulsed-field gel electrophoresis.
Setting
A hemodialysis center in Maryland.
Results
94 patients received dialysis on 27 machines; 10 (11%) of the patients had gram-negative bacteremias. Pathogens causing these infections were Enterobacter cloacae (n=6), Pseudomonas aeruginosa (n=4), and Escherichia coli (n=2); two patients had polymicrobial bacteremia. Factors associated with development of gram-negative …
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