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Purpose:

To assess combined hamartoma of the retina and retinal pigment epithelium with enhanced depth imaging optical coherence tomography.

Methods:

Retrospective, observational cases series in eight eyes of eight patients, with comparison between affected and unaffected eyes regarding enhanced depth imaging optical coherence tomography features of tumor, fovea, and choroid.

Results:

The mean age at presentation was 7 years. The tumor was macular (n= 5) or extramacular (n= 3). Enhanced depth imaging optical coherence tomography revealed irregularities in inner retina (n= 8) and/or all retinal layers (n= 3), with epiretinal membrane (n= 8), causing an inner retinal sawtooth (mini-peak) pattern (n= 2), full thickness retinal folds (maxi-peak)(n= 3), or both (n= 3). In the 5 macular tumors, foveal retinal thickness measured mean 608 μm compared with 244 μm in the unaffected eye (P= 0.0004). Mean tumor …