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Various psychosocial interventions have been developed to reduce distress and improve quality of life (QoL) in patients with advanced cancer, many of which are traditional cognitive‐behavioral interventions (CBIs) or mindfulness‐based interventions (MBIs). The aims of this meta‐analysis were to determine and compare the overall effects of traditional CBIs and MBIs on distress and QoL in this population and to explore potential moderators of intervention efficacy.

A systematic search was conducted in CINAHL, Embase, PsycINFO, PubMed, and Web of Science. Randomized controlled trials (RCTs) comparing CBIs or MBIs to controls on distress and QoL outcomes were eligible for inclusion. Random effects meta‐analyses using standardized baseline to post‐intervention mean differences were calculated using Hedges's g. Meta‐regressions were used to compare intervention effects and …