作者
Smitha Rajaram, Andrew J Swift, Adam Telfer, Judith Hurdman, Helen Marshall, Eleanor Lorenz, David Capener, Christine Davies, Catherine Hill, Charlie Elliot, Robin Condliffe, Jim M Wild, David G Kiely
发表日期
2013/7/1
期刊
Thorax
卷号
68
期号
7
页码范围
677-678
出版商
BMJ Publishing Group Ltd
简介
Background
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism potentially curable by surgery. Perfusion scintigraphy is currently advocated as the imaging modality of choice to exclude CTEPH due to its high sensitivity. We have evaluated the diagnostic utility of lung perfusion MRI.
Methods
Consecutive patients attending a pulmonary hypertension referral centre undergoing lung perfusion MRI, perfusion scintigraphy, CT pulmonary angiography (CTPA) and right heart catheterisation within 14 days were identified.
Results
Of 132 patients, 78 were diagnosed as having CTEPH. Lung perfusion MRI correctly identified 76 patients as having CTEPH with an overall sensitivity of 97%, specificity 92%, positive predictive value 95% and negative predictive value 96% compared with perfusion scintigraphy (sensitivity 96%, specificity 90%) and CTPA (sensitivity 94 …
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S Rajaram, AJ Swift, A Telfer, J Hurdman, H Marshall… - Thorax, 2013