作者
Andrew J Swift, Smitha Rajaram, Judith Hurdman, Catherine Hill, Christine Davies, Tom W Sproson, Allison C Morton, Dave Capener, Charlie Elliot, Robin Condliffe, Jim M Wild, David G Kiely
发表日期
2013/10
期刊
JACC: Cardiovascular Imaging
卷号
6
期号
10
页码范围
1036-1047
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to develop a composite numerical model based on parameters from cardiac magnetic resonance (CMR) imaging for noninvasive estimation of the key hemodynamic measurements made at right heart catheterization (RHC).
Background
Diagnosis and assessment of disease severity in patients with pulmonary hypertension is reliant on hemodynamic measurements at RHC. A robust noninvasive approach that can estimate key RHC measurements is desirable.
Methods
A derivation cohort of 64 successive, unselected, treatment naive patients with suspected pulmonary hypertension from the ASPIRE (Assessing the Spectrum of Pulmonary Hypertension Identified at a Referral Centre) Registry, underwent RHC and CMR within 12 h. Predicted mean pulmonary arterial pressure (mPAP) was derived using multivariate regression analysis of CMR measurements. The model was tested …
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AJ Swift, S Rajaram, J Hurdman, C Hill, C Davies… - JACC: Cardiovascular Imaging, 2013