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Non‐technical summary  An excess production of liver glucose is common in patients with diabetes, and animal studies show that female rats who consume a high‐fat diet during pregnancy may give birth to offspring who are more likely to develop diabetes in adulthood. However, how this may be occurring remains poorly understood. The present study investigated the effect of a maternal high fat diet on fetal genes in the liver that control the production of glucose, and the potential regulatory mechanisms of these genes. We observed that pups of high fat‐fed dams were heavier and had higher blood glucose at the time of delivery than pups of dams fed the control diet. While the high fat‐fed dams themselves did not have increased blood glucose, their pups had higher expression of genes to make glucose in addition to elevated blood glucose. Our study demonstrates that exposure to a high fat diet during …