作者
Charles Laidi, M‐A d'Albis, Michèle Wessa, Julia Linke, ML Phillips, Marine Delavest, Frank Bellivier, Amelia Versace, Jorge Almeida, Samuel Sarrazin, Cyril Poupon, Katia Le Dudal, Claire Daban, Nora Hamdani, Marion Leboyer, Josselin Houenou
发表日期
2015/3
期刊
Acta Psychiatrica Scandinavica
卷号
131
期号
3
页码范围
223-233
简介
Objective
There is growing evidence that cerebellum plays a crucial role in cognition and emotional regulation. Cerebellum is likely to be involved in the physiopathology of both bipolar disorder and schizophrenia. The objective of our study was to compare cerebellar size between patients with bipolar disorder, patients with schizophrenia, and healthy controls in a multicenter sample. In addition, we studied the influence of psychotic features on cerebellar size in patients with bipolar disorder.
Method
One hundred and fifteen patients with bipolar I disorder, 32 patients with schizophrenia, and 52 healthy controls underwent 3 Tesla MRI. Automated segmentation of cerebellum was performed using FreeSurfer software. Volumes of cerebellar cortex and white matter were extracted. Analyses of covariance were conducted, and age, sex, and intracranial volume were considered as covariates.
Results
Bilateral …
学术搜索中的文章
C Laidi, MA d'Albis, M Wessa, J Linke, ML Phillips… - Acta Psychiatrica Scandinavica, 2015