作者
Paschalis Steiropoulos, Ioannis Kotsianidis, Evangelia Nena, Venetia Tsara, Evdoxia Gounari, Olga Hatzizisi, Georgios Kyriazis, Pandora Christaki, Marios Froudarakis, Demosthenes Bouros
发表日期
2009/4/1
期刊
Sleep
卷号
32
期号
4
页码范围
537-543
出版商
Oxford University Press
简介
Study Objectives
Several lines of evidence suggest immune system derangement in obstructive sleep apnea syndrome (OSAS) patients. However, no data exist on the long-term effect of continuous positive airway pressure (CPAP) treatment on systemic immunity. Hence, we sought to evaluate this effect on various immunological parameters in OSAS patients.
Design
Prospective case series.
Setting
Sleep unit of a general hospital.
Patients
Newly-diagnosed, nonsmoking, otherwise healthy OSAS male patients (n = 52) were evaluated on diagnosis and 6 months after CPAP treatment. According to compliance to CPAP use at 6-month follow-up, they were divided into 2 groups: group A (n = 32): good compliance (mean CPAP use ≥ 4 h/night); and group B (n = 20): poor compliance (mean CPAP use < 4 h/night …
引用总数
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P Steiropoulos, I Kotsianidis, E Nena, V Tsara… - Sleep, 2009