作者
Sonny Dhanani, Laura Hornby, Amanda van Beinum, Nathan B Scales, Melanie Hogue, Andrew Baker, Stephen Beed, J Gordon Boyd, Jennifer A Chandler, Michaël Chassé, Frederick D’Aragon, Cameron Dezfulian, Christopher J Doig, Frantisek Duska, Jan O Friedrich, Dale Gardiner, Teneille Gofton, Dan Harvey, Christophe Herry, George Isac, Andreas H Kramer, Demetrios J Kutsogiannis, David M Maslove, Maureen Meade, Sangeeta Mehta, Laveena Munshi, Loretta Norton, Giuseppe Pagliarello, Tim Ramsay, Katerina Rusinova, Damon Scales, Matous Schmidt, Andrew Seely, Jason Shahin, Marat Slessarev, Derek So, Heather Talbot, Walther NKA van Mook, Petr Waldauf, Matthew Weiss, Jentina T Wind, Sam D Shemie
发表日期
2021/1/28
期刊
New England Journal of Medicine
卷号
384
期号
4
页码范围
345-352
出版商
Massachusetts Medical Society
简介
Background
The minimum duration of pulselessness required before organ donation after circulatory determination of death has not been well studied.
Methods
We conducted a prospective observational study of the incidence and timing of resumption of cardiac electrical and pulsatile activity in adults who died after planned withdrawal of life-sustaining measures in 20 intensive care units in three countries. Patients were intended to be monitored for 30 minutes after determination of death. Clinicians at the bedside reported resumption of cardiac activity prospectively. Continuous blood-pressure and electrocardiographic (ECG) waveforms were recorded and reviewed retrospectively to confirm bedside observations and to determine whether there were additional instances of resumption of cardiac activity.
Results
A total of 1999 patients were screened, and 631 were included in the study. Clinically reported …
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S Dhanani, L Hornby, A van Beinum, NB Scales… - New England Journal of Medicine, 2021