查看文章

In article number 1800209, Lauren Zavan et al. examine the proteome of Helicobacter pylori and their outer membrane vesicles (OMVs) produced throughout bacterial growth to determine how growth stage regulates their cargo composition. Analysis of OMVs produced by H. pylori reveal that growth stage affects the size, composition and protein selection into OMVs. The heat abundance map shows the proteome of OMVs differed from that of their parent bacterium, and changes throughout bacterial growth. These findings identify that bacterial growth stage regulates protein cargo selection into OMVs.