作者
Joshua Wang, Kate Beecher, Fatemeh Chehrehasa, Hayley Moody
发表日期
2023/4/1
来源
Reviews in the Neurosciences
卷号
34
期号
3
页码范围
295-311
出版商
De Gruyter
简介
Disordered eating can underpin a number of debilitating and prevalent chronic diseases, such as obesity. Broader advances in psychopharmacology and biology have motivated some neuroscientists to address diet-induced obesity through reductionist, pre-clinical eating investigations on the rodent brain. Specifically, chemogenetic and optogenetic methods developed in the 21st century allow neuroscientists to perform in vivo, region-specific/projection-specific/promoter-specific circuit manipulations and immediately assess the impact of these manipulations on rodent feeding. These studies are able to rigorously conclude whether a specific neuronal population regulates feeding behaviour in the hope of eventually developing a mechanistic neuroanatomical map of appetite regulation. However, an artificially stimulated/inhibited rodent neuronal population that changes feeding behaviour does not necessarily …
学术搜索中的文章
J Wang, K Beecher, F Chehrehasa, H Moody - Reviews in the Neurosciences, 2023