作者
Florian B Mayr, Sachin Yende, Walter T Linde-Zwirble, Octavia M Peck-Palmer, Amber E Barnato, Lisa A Weissfeld, Derek C Angus
发表日期
2010/6/23
期刊
Jama
卷号
303
期号
24
页码范围
2495-2503
出版商
American Medical Association
简介
Context
Severe sepsis, defined as infection complicated by acute organ dysfunction, occurs more frequently and leads to more deaths in black than in white individuals. The optimal approach to minimize these disparities is unclear.
Objective
To determine the extent to which higher severe sepsis rates in black than in white patients are due to higher infection rates or to a higher risk of acute organ dysfunction.
Design, Setting, and Participants
Analysis of infection-related hospitalizations from the 2005 hospital discharge data of 7 US states and infection-related emergency department visits from the 2003-2007 National Hospital Ambulatory Care Survey.
Main Outcome Measure
Age- and sex-standardized severe sepsis and infection hospitalization rates and the risk of acute organ dysfunction.
Results
Of 8 661 227 non–childbirth-related discharges, 2 261 857 were associated with an infection, and of these, 381 787 (16.8 …
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FB Mayr, S Yende, WT Linde-Zwirble, OM Peck-Palmer… - Jama, 2010