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Alzheimer’s disease (AD)‐related brain pathology is observed in participants within the normal ranges of cognitive assessments (Delacourte et al., 1999). Consequently, there is increased interest in subjective cognitive decline (SCD), a self‐experienced decline in cognition, as an early risk factor (Jessen et al., 2014). SCD is associated with earlier conversion to mild cognitive impairment (MCI) and AD (Jessen et al., 2010; Reisberg et al., 2010), poorer performance on cognitive tasks, and cortical thinning in AD‐related regions (Schultz et al., 2015; Sánchez‐Benavides et al., 2018). Women with surgical menopause prior to age 50 have an increased risk of AD (Rocca et al., 2007). Women with bilateral salpingo‐oophorectomy (BSO) without estradiol (E2) therapy in mid‐life show decreases in WM performance and volumetric declines in the frontal cortex and hippocampus compared to controls (Almey et …