作者
Yuan Yee Lee, Evelyn Saba, Muhammad Irfan, Minki Kim, Jireh Yi-Le Chan, Byeong Seon Jeon, Sung Keun Choi, Man Hee Rhee
发表日期
2019/2/15
期刊
Phytomedicine
卷号
54
页码范围
169-181
出版商
Urban & Fischer
简介
Background
Different processing conditions alter the ginseng bioactive compounds, promoting or reducing its anti-inflammatory effects. We compared black ginseng (BG) – that have been steamed 5 times – with red ginseng (RG).
Hypothesis/ Purpose
To compare the anti-inflammatory activities and the anti-nociceptive properties of RG and BG.
Methods
Nitric Oxide (NO) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide (MTT) assay, quantitative Reverse Transcriptase-Polymerase Chain Reaction (qRT-PCR), western blot, xylene-induced ear edema, carrageenan-induced paw edema
Results
The ginsenoside contents were confirmed using high-performance liquid chromatography (HPLC) and has been altered through increased processing. The highest concentration of these extracts inhibited NO production to near-basal levels in lipopolysaccharide (LPS)-stimulated RAW 264.7 without exhibiting …
学术搜索中的文章
YY Lee, E Saba, M Irfan, M Kim, J Yi-Le Chan, BS Jeon… - Phytomedicine, 2019