作者
JV Llau, FJ Acosta, G Escolar, E Fernández-Mondéjar, E Guasch, P Marco, P Paniagua, JA Paramo, M Quintana, P Torrabadella
发表日期
2015/11/1
期刊
Medicina Intensiva (English Edition)
卷号
39
期号
8
页码范围
483-504
出版商
Elsevier Doyma
简介
Massive haemorrhage is common and often associated with high morbidity and mortality. We perform a systematic review of the literature, with extraction of the recommendations from the existing evidences because of the need for its improvement and the management standardization. From the results we found, we wrote a multidisciplinary consensus document. We begin with the agreement in the definitions of massive haemorrhage and massive transfusion, and we do structured recommendations on their general management (clinical assessment of bleeding, hypothermia management, fluid therapy, hypotensive resuscitation and damage control surgery), blood volume monitoring, blood products transfusion (red blood cells, fresh frozen plasma, platelets and their best transfusion ratio), and administration of hemostatic components (prothrombin complex, fibrinogen, factor VIIa, antifibrinolytic agents).
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