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Sir, Screening of blood is now mandatory for many diseases and is undertaken routinely in blood banks. Many studies have been done on human immunodeficiency virus (HIV), syphillis, Australia antigen (HBsAg), hepatiis C virus (HCV) separately, but the knowledge about the interrelationship between these transfusion transmitted diseases (TTD’s) is limited, the present study was undertaken to find out the prevalence and correlation between various infectious markers in healthy blood donors.