作者
Elke Hunsche, Thomas Krieg, Barbara Schwierin, Daniel Rosenberg, B Raffier, M Hirschi, F Trautinger, P Schmidt, M Stetter, M Hundstorfer, V Reinhart, B Monshi, D Pirkhammer, L Richter, N Hamberger, S Metz, R Feldmann, K Semmelweis, K Lackner, N Tomi, H Kolle, F Hafner, M Brodmann, M Kuen-Spiegel, G Minmair, PM Heil, H Broil, G Holzer, X Illmer, B Rintelen, J Sautner, M Takacs, M Thun, I Zemanova, T Soukup, A Smrzova, J Bohmova, L Prochazkova, P Nemec, Z Fojtik, D Suchy, R Becvar, AB Olsen, KH Sondergaard, KL Vidqvist, S Madaule, N Beneton, H Maillard, H Charlanne, F GranelBrocard, E Hachulla, PY Hatron, N Jourdain, M Lambert, D Launay, S Morell, G Woijtasik, F Skowron, T Zenone, A Dadban, C Lok, D Ferrandiz, N MagyBertrand, MP Moiton, A Taieb, S Balquiere, E Belin, C Droitcourt, S Julien, S Prey, C Boulon, J Constans, MS Doutre, E Kostrzwewa, C Richez, M Greco, L Misery, B Sassolas, E Collet, S Berthier, V Leguy-Seguin, B Imbert, P Carpentier, S Blaise, A Couraud, V Doeffel-Hantz, A Spars, H Bezanahary, N Boussely, S Dumonteil, AL Fauchais, G Goudran, V Loustaud-Ratti, P Manea, E Vidal, B Coppere, H DesmursClavel, MH Girard-Madoux, A Hot, J Ninet, B Granel, JD Cohen, A Keynote, A Khau van Kien, A Le Quellec, S Riviere, P Rullier, D Bessis, C Farcas, V Bravetti, T Moline, D Wahl, S Zuily, F Granel-Brocard, C Agard, C Durant, JG Fuzibet, V Queyrel, A Berezne, L Guillevin, L Mouthon, J Cabane, K Tiev, C Toledano, I Lazareth, U Michon-Pasturel, P Priollet, Z Reguiai, C CazaletsLacoste, P Jego, A Letremy, A Perlat, AB Duval-Modeste, E Chatelus, H Chiffot, J Sibillia, C Sordet, D Adoue, B Couret, G Moulis, G Pugnet, L Sailler, E Diot, F Gaches, D Farge, H Keshtmand, C Frances, A von Elling, D Bora, J Ebel
发表日期
2013
期刊
Clinical and experimental rheumatology
卷号
31
期号
2 Suppl 76
页码范围
71-80
出版商
Pacini Editore srl
简介
OBJECTIVES
Digital ulcers (DUs) are frequent manifestations of systemic scleroderma (SSc). This study assessed functional limitations due to DUs among patients enrolled in the Digital Ulcer Outcome (DUO) Registry, an international, multicentre, observational registry of SSc patients with DU disease. METHODS
Patients completed at enrolment a DU-specific functional assessment questionnaire with a 1-month recall period, measuring impairment in work and daily activities, and hours of help needed from others. Physician-reported clinical parameters were used to describe the population. For patients who completed at least part of the questionnaire, descriptive analyses were performed for overall results, and stratified by number of DUs at enrolment. RESULTS
This study included 2327 patients who completed at least part of the questionnaire. For patients with 0, 1-2, and≥ 3 DUs at enrolment, mean overall work impairment during the prior month among employed/self-employed patients was 28%, 42%, and 48%, respectively. Across all included patients, ability to perform daily activities was impaired on average by 35%, 54%, and 63%, respectively. Patients required a mean of 2.0, 8.7, and 8.8 hours of paid help and 17.0, 35.9, and 63.7 hours of unpaid help, respectively, due to DUs in the prior month. Patients with DUs had more complications and medication use than patients with no DUs. CONCLUSIONS
With increasing number of DUs, SSc patients reported more impairment in work and daily activities and required more support from others.学术搜索中的文章
E Hunsche, T Krieg, B Schwierin, D Rosenberg… - Clinical and experimental rheumatology, 2013