作者
Matteo Lambertini, Valeria Fontana, Claudia Massarotti, Francesca Poggio, Chiara Dellepiane, Giuseppina Iacono, Annalisa Abate, Loredana Miglietta, Chiara Ferreccio, Maria Carolina Pescio, Benedetta Conte, Eva Blondeaux, Claudia Bighin, Alessia D'Alonzo, Marina Vaglica, Elisa Zanardi, Francesco Boccardo, Alberto Ballestrero, Paola Anserini, Lucia Del Mastro
发表日期
2018/10/1
期刊
The Breast
卷号
41
页码范围
51-56
出版商
Churchill Livingstone
简介
Background
Despite the availability of different strategies for ovarian function and/or fertility preservation in young breast cancer patients candidates for chemotherapy, limited data are available on patients’ actual need of these options.
Patients and methods
The PREFER study is a prospective cohort study including premenopausal women with newly diagnosed early stage breast cancer between the age of 18 and 45 years and candidates for chemotherapy. The study aimed to investigate patients' preferences and their choices of the different available strategies for ovarian function and/or fertility preservation (i.e. acceptance rate) and reasons for refusal.
Results
A total of 131 consecutive patients referred from a single breast unit were included. Median age was 38.9 years with 92 patients (70.3%) diagnosed at ≤ 40 years. The majority of patients (122, 93.1%) were concerned about the risk of treatment-induced …
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M Lambertini, V Fontana, C Massarotti, F Poggio… - The Breast, 2018