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More than 50% of patients with increased troponin levels after non‐cardiac surgery have an impaired endothelial function pre‐operatively. Non‐invasive markers of endothelial function have been developed for the assessment of endothelial dysfunction. The aim of this paper was to systematically review the literature to evaluate the association between non‐cardiac surgery and non‐invasive markers of endothelial function.

A systematic search was conducted in MEDLINE, EMBASE and Cochrane Library Database according to the PRISMA guidelines. Endothelial dysfunction was described only with non‐invasive measurements done both pre‐ and post‐operatively and published in English. All types of non‐cardiac surgery and both men and women of all ages were included.

We found 1722 eligible studies in our search, and of these, five studies fulfilled our inclusion and exclusion …