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Discussion| Previous studies have shown high spontaneous clearance rates regarding NMSC after biopsy. 2-4 The ability to predict cancer clearance based on lesion and patient characteristics would enable patients to avoid unnecessary surgical procedures and would allow health care resources to be used more efficiently. Residual cancer existed in the majority of cases of NMSC in our study. The cases of SCC showed higher rates of spontaneous clearance (42 of 73 cases [57.5%]) than did the cases of BCC (34 of 110 cases [30.9%]). No patient-specific risk factors were identified. There was a trend toward clearance of lesions with longer wait times between biopsy and excision, which suggests that close clinical surveillance may be appropriate for some low-risk lesions. Surgeons had difficulty predicting the persistence of cancer based on the appearance of the biopsy scar alone, regardless of experience …