作者
Martin Lambert, Thomas Bock, Daniel Schöttle, Dietmar Golks, Klara Meister, Liz Rietschel, Alexandra Bussopulos, Marietta Frieling, Michael Schödlbauer, Marc Burlon, Christian G Huber, Gunda Ohm, Manoshi Pakrasi, Michael Sadre Chirazi-Stark, Dieter Naber, Benno G Schimmelmann
发表日期
2010/3/23
期刊
The Journal of clinical psychiatry
卷号
71
期号
10
页码范围
1421
出版商
Physicians Postgraduate Press, Inc.
简介
Objective: The ACCESS trial examined the 12-month effectiveness of continuous therapeutic assertive community treatment (ACT) as part of integrated care compared to standard care in a catchment area comparison design in patients with schizophrenia spectrum disorders treated with quetiapine immediate release.
Method: Two catchment areas in Hamburg, Germany, with similar population size and health care structures were assigned to offer 12-month ACT as part of integrated care (n= 64) or standard care (n= 56) to 120 patients with first-or multiple-episode schizophrenia spectrum disorders (Structured Clinical Interview for DSM-IV Axis I Disorders criteria); multiple-episode patients were restricted to those with a history of relapse due to medication nonadherence. The primary outcome was time to service disengagement. Secondary outcomes comprised medication nonadherence, improvements of symptoms …
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M Lambert, T Bock, D Schöttle, D Golks, K Meister… - The Journal of clinical psychiatry, 2010