作者
Catherine M Hill, Hazel J Evans, Heather Elphick, Michael Farquhar, Ruth M Pickering, Ruth Kingshott, Jane Martin, Janine Reynolds, Anna Joyce, Carla Rush, Johanna C Gavlak, Paul Gringras
发表日期
2016/11/1
期刊
Sleep medicine
卷号
27
页码范围
99-106
出版商
Elsevier
简介
Background
Children with Down syndrome (DS) are vulnerable to obstructive sleep apnoea (OSA) because of their unique craniofacial anatomy and hypotonia. Understanding the predictors of OSA in DS may enable targeted screening.
Methods
Children with DS (n = 202) aged from six months to below six years (110 boys) were recruited from three UK children's hospitals. The clinical assessment included height, weight and tonsillar size. The parents either set up cardiorespiratory polygraphy at home or chose laboratory studies. Studies with less than four hours of interpretable data were repeated where possible. American Academy of Sleep Medicine (AASM) 2012 scoring criteria were used to derive an obstructive apnoea/hypopnoea index (OAHI). Predictors of moderate to severe OSA were examined.
Results
In total, 188/202 (93%) participants were successfully studied. Of these, 169 studies were completed at …
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CM Hill, HJ Evans, H Elphick, M Farquhar… - Sleep medicine, 2016