作者
Seraina Sallenbach, Steffen Thiel, Christoph Aebi, Margrith Otth, Susanna Bigler, Jens C Jensenius, Luregn J Schlapbach, Roland A Ammann
发表日期
2011/6
期刊
Pediatric Allergy and Immunology
卷号
22
期号
4
页码范围
424-430
出版商
Blackwell Publishing Ltd
简介
To cite this article: Sallenbach S, Thiel S, Aebi C, Otth M, Bigler S, Jensenius JC, Schlapbach LJ, Ammann RA. Serum concentrations of lectin‐pathway components in healthy neonates, childrens and adults: mannan‐binding lectin (MBL), M‐, L‐, and H‐ficolin, and MBL‐associated serine protease‐2 (MASP‐2).Pediatr Allergy Immunol 2011;: 424–430.
Abstract
This study aimed to measure serum concentrations of five lectin‐pathway components, mannan‐binding lectin (MBL), M‐ficolin, L‐ficolin, H‐ficolin, and MBL‐associated serine protease‐2 (MASP‐2), in healthy neonates and children, to determine if they change with age and to compare them with serum concentrations in healthy adults. Concentrations were measured in 141 preterm and 30 term neonates, in 120 children including infants and adolescents, and in 350 adults (97 for L‐ficolin) by inhouse time‐resolved immunofluorometric assays or …
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