作者
Niek B Achten, Claus Klingenberg, William E Benitz, Martin Stocker, Luregn J Schlapbach, Eric Giannoni, Robin Bokelaar, Gertjan JA Driessen, Petter Brodin, Sabita Uthaya, Annemarie MC van Rossum, Frans B Plötz
发表日期
2019/11/1
来源
JAMA pediatrics
卷号
173
期号
11
页码范围
1032-1040
出版商
American Medical Association
简介
Importance
The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on the effectiveness and safety of the EOS calculator is essential to inform clinicians considering implementation.
Objective
To assess the association between management of neonatal EOS guided by the neonatal EOS calculator (compared with conventional management strategies) and reduction in antibiotic therapy for newborns.
Data Sources
Electronic searches in MEDLINE, Embase, Web of Science, and Google Scholar were conducted from 2011 (introduction of the EOS calculator model) through January 31, 2019.
Study Selection
All studies with original data that compared management guided by the EOS calculator with conventional management strategies for allocating antibiotic therapy to newborns suspected to have EOS were …
学术搜索中的文章
NB Achten, C Klingenberg, WE Benitz, M Stocker… - JAMA pediatrics, 2019