作者
Luregn J Schlapbach, Maude Aebischer, Mark Adams, Giancarlo Natalucci, Jan Bonhoeffer, Philipp Latzin, Mathias Nelle, Hans Ulrich Bucher, Beatrice Latal, Swiss Neonatal Network and Follow-Up Group
发表日期
2011/8/1
期刊
Pediatrics
卷号
128
期号
2
页码范围
e348-e357
出版商
American Academy of Pediatrics
简介
OBJECTIVE
Neonatal sepsis causes high mortality and morbidity in preterm infants, but less is known regarding the long-term outcome after sepsis. This study aimed to determine the impact of sepsis on neurodevelopment at 2 years' corrected age in extremely preterm infants.
PATIENTS AND METHODS
This was a multicenter Swiss cohort study on infants born between 2000 and 2007 at 2407 to 2767 weeks' gestational age. Neurodevelopmental outcome was assessed with the Bayley Scales of Infant Development–II. Neurodevelopmental impairment (NDI) was defined as a Mental or Psychomotor Developmental Index lower than 70, cerebral palsy (CP), or visual or auditory impairment.
RESULTS
Of 541 infants, 136 (25%) had proven sepsis, 169 (31%) had suspected sepsis, and 236 (44%) had no signs of infection. CP occurred in 14 of 136 (10%) infants with …
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