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Background. Comorbidity is the single most important determinant of outcome in patients on renal replacement therapy. The aims of this study were to evaluate a semi‐quantitative approach to comorbidity scoring in predicting survival of patients commencing peritoneal dialysis (PD), and to establish the interaction between this and other known predictors of patient outcome, in particular membrane function, residual renal function (RRF) and plasma albumin.

Methods. Comorbidity was recorded in a prospective, single centre cohort study of 303 patients commencing on PD. Using seven disease domains, chosen to reflect the dominance of cardiovascular morbidity in the end‐stage renal failure population, comorbidity was graded as ‘0’ when absent, ‘1’ when one or two, and ‘2’ when three or more conditions were present. The Wright comorbidity index, which includes age within the scoring …