作者
Xinyu Zhou, Kurt D Michael, Yiyun Liu, Cinzia Del Giovane, Bin Qin, David Cohen, Salvatore Gentile, Peng Xie
发表日期
2014/12
来源
BMC psychiatry
卷号
14
页码范围
1-9
出版商
BioMed Central
简介
Background
Current guidelines for treatment-resistant depression in adolescents remain inadequate. This study aimed to systematically review the management of treatment-resistant depression in adolescent patients.
Methods
We conducted an electronic database search of PUBMED, EMBASE, Cochrane, Web of Science and PsycINFO for studies with adolescent treatment-resistant depression published up to January 2014. Treatment-resistant depression was defined as failure to respond to at least one course of psychological or pharmacological treatment for depression with an adequate dosage, duration, and appropriate compliance during the current illness episode. The Cochrane risk-of-bias method was used to assess the quality of randomized controlled trials. A meta-analysis of all active treatments was conducted …
学术搜索中的文章
X Zhou, KD Michael, Y Liu, C Del Giovane, B Qin… - BMC psychiatry, 2014