作者
Daniel YC Heng, Wanling Xie, Meredith M Regan, Lauren C Harshman, Georg A Bjarnason, Ulka N Vaishampayan, Mary Mackenzie, Lori Wood, Frede Donskov, Min-Han Tan, Sun-Young Rha, Neeraj Agarwal, Christian Kollmannsberger, Brian I Rini, Toni K Choueiri
发表日期
2013/2/1
期刊
The lancet oncology
卷号
14
期号
2
页码范围
141-148
出版商
Elsevier
简介
Background
The International Metastatic Renal-Cell Carcinoma Database Consortium model offers prognostic information for patients with metastatic renal-cell carcinoma. We tested the accuracy of the model in an external population and compared it with other prognostic models.
Methods
We included patients with metastatic renal-cell carcinoma who were treated with first-line VEGF-targeted treatment at 13 international cancer centres and who were registered in the Consortium's database but had not contributed to the initial development of the Consortium Database model. The primary endpoint was overall survival. We compared the Database Consortium model with the Cleveland Clinic Foundation (CCF) model, the International Kidney Cancer Working Group (IKCWG) model, the French model, and the Memorial Sloan-Kettering Cancer Center (MSKCC) model by concordance indices and other measures of …
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DYC Heng, W Xie, MM Regan, LC Harshman… - The lancet oncology, 2013