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High intake of dietary fat has been implicated in the incidence of cardiovascular disease. The effects of 3 Nigerian dietary oils (crude palm oil, refined palm olein of Malaysian origin and crude groundnut oil) were assessed on plasma lipid profile of wistar albino rats. Twenty rats were randomly divided into four groups of 5 per group. Rats in the control group were given normal feeds only while in addition the treated groups were given 1 mL of additional crude palm oil, groundnut oil and refined palm olein oils as supplement adlibitum for 28 days. Results showed decline in High density lipoprotein (HDL-C), Low density lipoprotein cholesterol (LDL-C) and Total Cholesterol (TC) concentrations in all the treated groups compared to control group. HDL-C reduction was significant only in groundnut oil treated group (p<0.05) while LDL-C percentage concentration reduction were 14.6, 44.9 and 10.8% and TC …