作者
Randy L King, Yunbo Liu, Subha Maruvada, Bruce A Herman, Keith A Wear, Gerald R Harris
发表日期
2011/7/14
期刊
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
卷号
58
期号
7
页码范围
1397-1405
出版商
IEEE
简介
A tissue-mimicking material (TMM) for the acoustic and thermal characterization of high-intensity focused ultrasound (HIFU) devices has been developed. The material is a high-temperature hydrogel matrix (gellan gum) combined with different sizes of aluminum oxide particles and other chemicals. The ultrasonic properties (attenuation coefficient, speed of sound, acoustical impedance, and the thermal conductivity and diffusivity) were characterized as a function of temperature from 20 to 70°C. The backscatter coefficient and nonlinearity parameter B/A were measured at room temperature. Importantly, the attenuation coefficient has essentially linear frequency dependence, as is the case for most mammalian tissues at 37°C. The mean value is 0.64f 0.95 dB·cm -1 at 20°C, based on measurements from 2 to 8 MHz. Most of the other relevant physical parameters are also close to the reported values, although …
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RL King, Y Liu, S Maruvada, BA Herman, KA Wear… - IEEE transactions on ultrasonics, ferroelectrics, and …, 2011