作者
Ronald B Postuma, Jacques Y Montplaisir, Amélie Pelletier, Yves Dauvilliers, Wolfgang Oertel, A Iranzo, Luigi Ferini-Strambi, I Arnulf, B Hogl, R Manni, T Miyamoto, G Mayer, K Stiasny-Kolster, MONICA Puligheddu, Y Ju, P Jennum, K Sonka, J Santamaria, ML Fantini, M Zucconi, S Leu-Semenescu, B Frauscher, M Terzaghi, M Miyamoto, MM Unger, V Cochen De Cock, C Wolfson
发表日期
2012/7/31
期刊
Neurology
卷号
79
期号
5
页码范围
428-434
出版商
Lippincott Williams & Wilkins
简介
Objective
Idiopathic REM sleep behavior disorder is a parasomnia characterized by dream enactment and is commonly a prediagnostic sign of parkinsonism and dementia. Since risk factors have not been defined, we initiated a multicenter case-control study to assess environmental and lifestyle risk factors for REM sleep behavior disorder.
Methods
Cases were patients with idiopathic REM sleep behavior disorder who were free of dementia and parkinsonism, recruited from 13 International REM Sleep Behavior Disorder Study Group centers. Controls were matched according to age and sex. Potential environmental and lifestyle risk factors were assessed via standardized questionnaire. Unconditional logistic regression adjusting for age, sex, and center was conducted to investigate the environmental factors.
Results
A total of 694 participants (347 patients, 347 controls) were recruited. Among cases, mean age was …
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RB Postuma, JY Montplaisir, A Pelletier, Y Dauvilliers… - Neurology, 2012
