作者
LiYueh Hsu, Alex Natanzon, Peter Kellman, Glenn A Hirsch, Anthony H Aletras, Andrew E Arai
发表日期
2006/3
期刊
Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine
卷号
23
期号
3
页码范围
298-308
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Purpose
To develop a computer algorithm to measure myocardial infarct size in gadoliniumenhanced magnetic resonance (MR) imaging and to validate this method using a canine histopathological reference.
Materials and Methods
Delayed enhancement MR was performed in 11 dogs with myocardial infarction (MI) determined by triphenyltetrazolium chloride (TTC). Infarct size on in vivo and ex vivo images was measured by a computer algorithm based on automated feature analysis and combined thresholding (FACT). For comparison, infarct size by human manual contouring and simple intensity thresholding (based on two standard deviation [2SD] and full width at half maximum [FWHM]) were studied.
Results
Both in vivo and ex vivo MR infarct size measured by the FACT algorithm correlated well with TTC (R = 0.95–0.97) and showed no significant bias on Bland Altman analysis (P = not significant …
引用总数
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